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Antimicrobial activity of new phorbins from Jatropha curcas Linn. (Euphorbiaceae) leaves


Villasenor IM, Carino FA


The crude methanol extract of Jatropha curcas leaves exhibited activity against Staphylococcus aureus, Bacillus subtilis, Mycobacterium phlei, Candida albicans, and Trichophyton mentagrophytes but was inactive against Escherichia coli, Pseudomonas aeruginosa, and Saccharomyces cerevisiae. In a bioassay-directed fractionation, two new phorbins were isolated and analysed by spectroscopic methods. Isolate 1 was characterized as an analogue of pheophytin b with a phytyl moiety containing three double bonds which are at positions P2/P3, P6/P7, and P10/P11. Compound 2 was characterized as methyl pheophorbide a with 132-OH and 17- and 17(1)-CH3 moieties. It is active against Serratia marcescens.


Plant local nameTubang-bakod
Scientific nameJatropha curcas
Is local study?
"" plant grouping3
Abstract availabilityYes
"" plant name IDTBB79
Type of studyFor classification
Full text available?
Full citationVillasenor IM, Carino FA. Antimicrobial activity of new phorbins from Jatropha curcas Linn. (Euphorbiaceae) leaves. Z Naturforsch C 2011;66(9-10):441-446.